trans-2-(3-chloro-5-fluorophenyl)cyclopropane-1-carboxylic acid - Names and Identifiers
trans-2-(3-chloro-5-fluorophenyl)cyclopropane-1-carboxylic acid - Physico-chemical Properties
trans-2-(3-chloro-5-fluorophenyl)cyclopropane-1-carboxylic acid - Introduction
trans-2-(3-chloro-5-fluorophenyl)cyclopropane-1-carboxylic acid is an organic compound with the chemical formula C10H7ClF2O2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Melting Point: about 110-114 ℃
-Solubility: Soluble in ethanol and dichloromethane, slightly soluble in water
Use:
- trans-2-(3-chloro-5-fluorophenyl)cyclopropane-1-carboxylic acid has certain applications in the field of medicine. It can be used as a raw material or intermediate to synthesize anti-cancer drugs, weight loss drugs, antiviral drugs, etc.
Method:
-A method for synthesizing trans-2-(3-chloro-5-fluorophenyl)cyclopropane-1-carboxylic acid is prepared by oxidation reaction. Specifically, 3-chloro-5-fluorobenzaldehyde is first condensed with acetone to produce 3-chloro-5-fluorophenyl-acetone, it is then reduced to 3-chloro-5-fluorophenyl-2-propanol by hydrogenation. Finally, 3-chloro-5-fluorophenyl-2-propanol is cyclopropanated with Butyronitrile to produce the target product trans-2-(3-chloro-5-fluorophenyl)cyclopropane-1-carboxylic acid.
Safety Information:
- trans-2-(3-chloro-5-fluorophenyl)cyclopropane-1-carboxylic acid is an organic compound, you need to pay attention to the correct use and storage methods.
-The compound may cause irritation to the eyes, skin and respiratory tract, so the necessary protective measures should be taken during handling, including wearing appropriate protective glasses, gloves and masks.
-When using, care should be taken to avoid mixing with strong oxidants and strong acids to avoid dangerous chemical reactions.
-When storing, keep it in a dry, well-ventilated place, away from fire and high temperature, and avoid contact with air, water or humidity.
Last Update:2024-04-09 21:00:56